They will be replaced on the roster by linebackers DeMarquis Gates and Terrell Lewis and defensive end Jalyn Holmes, all of whom were signed from the practice squad.
Jenkins exited last Sunday's game against the Lions with a neck injury. The 2021 second-round pick appeared in 13 games with 11 starts this season, playing 73 percent of the offensive snaps to date.
Schofield replaced Jenkins in Detroit before injuring his knee in the second quarter. The eight-year NFL veteran appeared in 12 games with five starts this season. Prior to joining the Bears this year, Schofield played in 102 games with 81 starts over seven seasons with the Broncos (2015-16), Chargers (2017-19, 2021) and Panthers (2020).
Blackwell entered the NFL this year with the Eagles as an undrafted rookie from Duke. He was claimed by the Bears off waivers and appeared in all 16 games to this point with one start, registering 12 tackles on defense and a team-leading 11 stops on special teams.
Gates has appeared in one game this season, making his NFL debut Nov. 27 against the Jets. Prior to joining the Bears, he had been signed and cut by the NFL's Browns, Commanders and Vikings and also played in five other pro football leagues: the AAF, the XFL, the Spring League, the CFL and the USFL.
Lewis was signed to the Bears practice squad Dec. 20, five days after being waived by the Rams. He was selected by Los Angeles in the third round of the 2020 draft out of Alabama and played in 30 games with seven starts over three seasons, compiling 40 tackles, eight tackles-for-loss, one interception, 1.0 sack and one forced fumble.
Holmes was chosen by the Vikings in the fourth round of the 2018 draft out of Ohio State. He appeared in 33 games with 10 starts over four seasons with the Vikings (2018-20) and Saints (2021), registering 57 tackles, six tackles-for-loss, 1.0 sack and three pass breakups. Holmes spent part of the summer with the Giants and was signed to the Bears practice squad Oct. 4.