Bears quarterback Jay Cutler did not practice again Friday and was listed as doubtful for Sunday's game in Indianapolis, meaning that Brian Hoyer likely will make his third straight start.
Cutler sprained his right thumb in a Week 2 loss to the Eagles. He returned to practice on a limited basis last Wednesday but has missed all five of the Bears' workouts since that point.
Running back Jeremy Langford, nose tackle Eddie Goldman and cornerback Deiondre Hall all sat out Friday's practice with ankle injuries and were listed as doubtful for Sunday's game. Friday marked the first time that Hall was on the injury report this week.
Quarterback Brian Hoyer likely will make his third straight start.
"He rolled his ankle at some point late in practice [Thursday]," said coach John Fox. "It really didn't flare up until this morning."
Twelve Bears players were listed as questionable Friday, meaning that their availability for Sunday's game against the Colts is uncertain. Of that group, only receiver Eddie Royal (calf) and left tackle Charles Leno Jr. Jr. (illness) did not practice Friday.
Royal may still play even though he didn't practice all week.
"We don't have a 'no practice, no play' policy," Fox said. "It's just a matter of if we deem we're better with him than without him. We'll make that judgment. We have up to an hour-and-a-half before kickoff."
If Leno is unable to play, Fox revealed it's "more than likely" veteran Mike Adams would start in Leno's place, saying: "He's been that seventh guy active on game day. That's been the swing tackle position. That would probably be part of the contingency plan."
The other 10 players listed as questionable were limited in practice Friday: outside linebackers Leonard Floyd (calf) and Willie Young (knee/elbow), running back Ka'Deem Carey (hamstring), receiver Alshon Jeffery (knee), tight end Zach Miller (ribs), defensive end Jonathan Bullard (shoulder), inside linebackers Danny Trevathan (thumb) and Nick Kwiatkoski (elbow) and cornerbacks Tracy Porter (knee) and Sherrick McManis (hamstring).
Floyd sat out the final portion of last Sunday's win over the Lions after hurting his calf. He has also battled hamstring and shoulder issues. Asked Wednesday how the first-round draft pick can improve as a pass rusher, defensive coordinator Vic Fangio said: "to be healthy."
"I think that's true with every player; anytime they're not available and they're not out there, it's hard to say you're getting a lot better," Fox said. "Injuries are a part of the game. I look at it more like it tests your coaching. So we'll have to rise to the occasion."