Moore was a full participant in practice Friday after being limited Thursday due to an ankle injury he sustained in last Sunday's win over the Lions.
Moore was injured early in the second half but returned after missing a few plays. He later scored his second touchdown of the game on a 38-yard reception from Justin Fields, snapping a 13-13 tie in an eventual 28-13 win.
"Your best players have to be your hardest workers, but they've got to be your toughest too, and that's what he is," said coach Matt Eberflus. "He is a tough son of a gun. He's got everything you want from a leader. He doesn't have to say much and when he talks, everybody listens. It's really good to have him."
Brisker returned to practice on a limited basis Friday after sitting out Thursday with groin tightness.
Asked about Brisker's availability, Eberflus said: "We'll see where it goes. He was out there limited today, but hopefully trending in the right direction."
For the Browns, center Ethan Pocic (stinger) and defensive end Ogbo Okoronkwo (pectoral) have been ruled out; and defensive tackle Jordan Elliott (concussion), linebacker Anthony Walker (knee) and cornerback Denzel Ward (shoulder) are questionable.
With Pocic sidelined, Cleveland will play without three of its regular starting offensive linemen. Left tackle Jedrick Wills has been on injured reserve since Nov. 7 and will not return this season, while rookie right tackle Dawand Jones suffered a season-ending knee injury Dec. 7 in practice.